To develop methods to improve the quality and reliability of data:

• Sample design
• Sample size calculations
• Advise on randomization methods
• Writing or reviewing of statistical analysis plan
• Conduction of statistical analyses according to pre-defined analysis plans
• Provision advice and support for statistical analysis
• Provision of centralized statistical monitoring
• Management of Independent Data Monitoring Committee (IDMC) meetings
• Provision statistical reports for IDMC meetings
• Contribution to the reports to the funders, regulators and sponsors
• Conduction of additional exploratory analyses
• Medical writing - Contribute significantly to drafting of manuscripts, abstracts and presentations